Characterization of carbon monoxide (CO) -induced delayed neuronal death in mice.

Exogenous carbon monoxide improves neuronal differentiation: a near-death experience

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

Delayed restricted diffusion in carbon monoxide leukoencephalopathy.

to a wide range of neurological symptoms, ranging from headaches, dizziness and altered mental status to coma. The basis for this is thought to be hypoxia. Carbon monoxide competes with oxygen for binding to hemoglobin (Hb) and once bound, shifts the oxyhemoglobin dissociation curve to the left, thus impairing off-loading of oxygen molecules, leading to hypoxia . A sizable minority of CO poison...

Delayed syndrome in carbon monoxide poisoning.

Acute carbon monoxide poisoning can lead to delayed manifestations. This has been called post-interval syndrome, which can present after an apparent period of normalcy following acute poisoning. We are reporting a patient who had an accidental exposure to carbon monoxide and presented later with all the manifestations of delayed poisoning. The various clinical manifestations and imaging finding...

Carbon monoxide-induced death and toxicity from charcoal briquettes.

The Medical Journal of Australia ISSN: 0025729X 17 September 2012 197 6 349-350 ©The Medical Journal of Australia 2012 www.mja.com.au Lessons from Practice combustion of carbon-containing ti ns of restricted oxygen supply, naces, unflued heaters, compr stoves, vehicle exhaust, welders, fuelled equipment, and building fir The mechanism of CO toxicity inhibition of oxygen binding to h This case h...

Death sequence in multiple carbon monoxide asphyxiations.